Preheat oven to 375°F (190°C) and grease a baking sheet.

Cook ground beef in a skillet over medium heat, breaking it up until browned. Drain excess fat.

Stir in cream cheese, cheddar, garlic powder, onion powder, salt, and pepper until fully combined.

Open biscuit dough, separate into individual pieces, and flatten each one.

Place a spoonful of the beef mixture in the center of each biscuit, seal tightly, and roll into balls.

Brush with melted butter, sprinkle with Parmesan, and bake for 12-15 minutes, until golden brown. Garnish with parsley and serve!