Preheat to 375°F (190°C). Line a baking sheet with parchment or grease lightly.
Mix turkey, mozzarella, bacon, pickles, garlic powder, onion powder, salt, and pepper in a bowl until well combined.
Separate biscuits and flatten each into a 3-inch round.
Place a heaping tablespoon of filling in the center of each round.
Fold dough over filling, pinch to seal, and roll into a ball. Place seam-side down on the sheet.
Bake 15–20 minutes until golden and cooked through.
Cool for 5 minutes before serving. Cheese will be hot.