Preheat your oven to 400°F (200°C). Line a baking sheet with parchment paper or lightly grease it with cooking spray to prevent sticking.
Wash the zucchinis thoroughly and slice them into 1/4-inch thick rounds or half-moons, depending on your presentation preference.
Place the sliced zucchini in a large mixing bowl. Drizzle with olive oil and toss to coat evenly. Sprinkle in garlic powder, onion powder, Italian seasoning, salt, and pepper. Stir until each piece is well-seasoned.
Spread the zucchini slices in a single layer on the prepared baking sheet. Avoid overlapping to ensure even cooking and crispy edges.
If you're using Parmesan cheese and breadcrumbs, sprinkle them generously over the zucchini slices.
Place the baking sheet in the oven and bake for 15–20 minutes. Zucchini should be fork-tender, with slightly crisp, golden edges. The cheese and breadcrumbs (if used) should be lightly browned and crisp.
Remove from the oven and serve immediately. These make a great snack, side dish, or topping for grain bowls and salads.