Boil salted water, cook bowtie pasta for 10–11 minutes until tender, then drain. Reserve 1/2 cup pasta water.
Season chicken with salt, pepper, garlic powder, onion powder, and Italian seasoning. Sear in olive oil over medium-high heat for 6–7 minutes per side until golden and cooked through (165°F).
Lower heat, add garlic and cook 1 minute. Stir in lemon zest, juice, and 1 tbsp butter to glaze. Remove chicken.
In the same skillet, melt remaining butter. Add cream and broth, simmer 2–3 minutes.
Stir in Parmesan until smooth. Adjust seasoning.
Toss pasta in sauce, adding pasta water if needed. Fold in chicken.
Garnish with parsley and extra Parmesan. Serve hot or cool for lunch prep.